Pre_GI: SWBIT SVG BLASTN

Query: NC_011244:746801 Borrelia recurrentis A1, complete genome

Lineage: Borrelia recurrentis; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Borrelia recurrentis isolated from adult patient with louse-borne relapsing fever in Ethiopia. Borrelia recurrentis is the causative agent of louse-borne relapsing fever. Prior to World War II, this organism was responsible for large disease outbreaks with a mortality of up to 40% in much of the world. Currently this disease is limited to parts of Africa, China, and Peru. B. recurrentis is transmitted when infected human body lice (Pediculus humanus) are crushed and their fluids contaminate mucous membranes or breaks in the skin. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another.

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BLASTN Alignment.txt

Subject: NC_003869:2143892 Thermoanaerobacter tengcongensis MB4, complete genome

Lineage: Caldanaerobacter subterraneus; Caldanaerobacter; Thermoanaerobacteraceae; Thermoanaerobacterales; Firmicutes; Bacteria

General Information: This organism was originally isolated from a hot spring in Tengcong, China, and is the type strain for the species. Genomic analysis indicates it is similar to Bacillus halodurans and that it has one of the most biased leading strand distribution of genes. Although the organism has not been observed to be motile or to sporulate, it does contain genes for both functions. The bacterium produces acetate and ethanol from glucose and cannot degrade xylan and cellulose.