Pre_GI: SWBIT SVG BLASTN

Query: NC_011244:746801 Borrelia recurrentis A1, complete genome

Lineage: Borrelia recurrentis; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Borrelia recurrentis isolated from adult patient with louse-borne relapsing fever in Ethiopia. Borrelia recurrentis is the causative agent of louse-borne relapsing fever. Prior to World War II, this organism was responsible for large disease outbreaks with a mortality of up to 40% in much of the world. Currently this disease is limited to parts of Africa, China, and Peru. B. recurrentis is transmitted when infected human body lice (Pediculus humanus) are crushed and their fluids contaminate mucous membranes or breaks in the skin. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another.

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BLASTN Alignment.txt

Subject: NC_000853:1480478 Thermotoga maritima MSB8, complete genome

Lineage: Thermotoga maritima; Thermotoga; Thermotogaceae; Thermotogales; Thermotogae; Bacteria

General Information: Rod-shaped thermophilic marine bacterium that metabolizes many simple and complex carbohydrates including glucose, sucrose, starch, cellulose, and xylan. This hyperthermophilic organism was originally isolated from a geothermal marine area near Vulcano, Italy. Thermotoga maritima is a hyperthermophile with an optimum growth temperature of 80 degrees C. This organism, a member of the Thermotogales, has the characteristic sheath-like envelope which extends beyond the cell wall. These organisms are heterotrophs are able to use a wide range of carbohydrates.