Query: NC_011206:2549132 Acidithiobacillus ferrooxidans ATCC 53993, complete genome Lineage: Acidithiobacillus ferrooxidans; Acidithiobacillus; Acidithiobacillaceae; Acidithiobacillales; Proteobacteria; Bacteria General Information: Acidithiobacillus ferrooxidans, formerly Thiobacillus ferrooxidans, is an acidophilic iron-oxidizing bacterium that is able to grow at a pH range of 1.3 to 4.0. This organism is often identified in acid mine drainage and as a member of microbial consortia involved in bioleaching. Acidithiobacillus ferrooxidans has been identified as the dominant microorganism in percolation and continuous flow mineral leaching bioreactors.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.