Query: NC_011144:1073944 Phenylobacterium zucineum HLK1, complete genome
Lineage: Phenylobacterium zucineum; Phenylobacterium; Caulobacteraceae; Caulobacterales; Proteobacteria; Bacteria
General Information: This organism was isolated from the human leukemia cell line K562. This facultative intracellular bacteria does not appear to alter the replication or morphology of the cell line.
Subject: NC_012808:921985 Methylobacterium extorquens AM1, complete genome
Lineage: Methylobacterium extorquens; Methylobacterium; Methylobacteriaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: First isolated in 1960 in Oxford, England, as an airborne contaminant growing on methylamine. This strain can grow on methylamine or methanol, but not methane. This organism is capable of growth on one-carbon compounds such as methanol. Methanol is oxidized to formaldehyde which is then used metabolically to generate either energy or biomass. These bacteria are commonly found in the environment, especially associated with plants which produce methanol when metabolizing pectin during cell wall synthesis. At least 25 genes are required for this complex process of converting methanol to formaldehyde and this specialized metabolic pathway is of great interest.