Pre_GI: SWBIT SVG BLASTN

Query: NC_011035:541560 Neisseria gonorrhoeae NCCP11945 chromosome, complete genome

Lineage: Neisseria gonorrhoeae; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Neisseria gonorrhoeae NCCP11945 was isolated in 2002 from a vaginal smear of a Korean patient. This is a multidrug-resistant strain. One of two pathogenic Neisseria, this species causes the sexually transmitted disease (STD) gonorrhea, which is the leading reportable STD in adults in the USA. This human-specific organism colonizes and invades the mucosal surface of the urogenital epithelium, crosses the epithelial barrier, and ends up multiplying on the basement membrane. Pathogenic functions include the antigenically variable type IV pilus and the opacity (Opa) proteins. The Opa proteins are responsible for the opaque colony phenotype due to the tight junctions between adjacent Neisseria, and are also responsible for tight adherence to host cells. This organism, like Neisseria meningitidis, is also naturally competent for DNA uptake.

Subject: NC_013169:2045000 Kytococcus sedentarius DSM 20547, complete genome

Lineage: Kytococcus sedentarius; Kytococcus; Dermacoccaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Country: USA; Temp: Mesophile; Temp: 28 - 36C; Habitat: Marine, Skin microflora. Strain DSM 20547, the type strain, is a free-living, nonmotile, Gram-positive bacterium, originally isolated from a marine environment in about 1944. It grows as spherical/coccoid and occurs predominantly in tetrads which can be arranged in cubical packets. It is non-encapsulated and does not form endospores, is strictly aerobic and chemoorganotrophic, requires methionine and other amino acids for growth, and grows well in NaCl at concentrations up to 10% (w/v). This organism is a normal commensal of human skin, however has been implicated in pitted keratolysis, pneumonia, and other opportunistic infections.