Query: NC_011035:1908000 Neisseria gonorrhoeae NCCP11945 chromosome, complete genome Lineage: Neisseria gonorrhoeae; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria General Information: Neisseria gonorrhoeae NCCP11945 was isolated in 2002 from a vaginal smear of a Korean patient. This is a multidrug-resistant strain. One of two pathogenic Neisseria, this species causes the sexually transmitted disease (STD) gonorrhea, which is the leading reportable STD in adults in the USA. This human-specific organism colonizes and invades the mucosal surface of the urogenital epithelium, crosses the epithelial barrier, and ends up multiplying on the basement membrane. Pathogenic functions include the antigenically variable type IV pilus and the opacity (Opa) proteins. The Opa proteins are responsible for the opaque colony phenotype due to the tight junctions between adjacent Neisseria, and are also responsible for tight adherence to host cells. This organism, like Neisseria meningitidis, is also naturally competent for DNA uptake.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Edwardsiella tarda is a Gram-negative member of the normal gut microflora of fish, humans, chickens and other animals. This organism is also a serious pathogen of marine and freshwater fish and has been isolated from channel catfish, Japanese eels, flounder, tilapia, and other economically important fish. Infection by this organism is characterized by septicemia, internal abscesses, and skin lesions. This disease is often associated with poor water quality and mortality in aquaculture can be high. Edwardsiella tarda also causes opportunistic infections in humans, most commonly gastroenteritis and wound infections. However, this organism has been isolated from cases of septicemia and meningitis, primarily in immunocompromised patients.