Pre_GI: SWBIT SVG BLASTN

Query: NC_011035:1908000 Neisseria gonorrhoeae NCCP11945 chromosome, complete genome

Lineage: Neisseria gonorrhoeae; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Neisseria gonorrhoeae NCCP11945 was isolated in 2002 from a vaginal smear of a Korean patient. This is a multidrug-resistant strain. One of two pathogenic Neisseria, this species causes the sexually transmitted disease (STD) gonorrhea, which is the leading reportable STD in adults in the USA. This human-specific organism colonizes and invades the mucosal surface of the urogenital epithelium, crosses the epithelial barrier, and ends up multiplying on the basement membrane. Pathogenic functions include the antigenically variable type IV pilus and the opacity (Opa) proteins. The Opa proteins are responsible for the opaque colony phenotype due to the tight junctions between adjacent Neisseria, and are also responsible for tight adherence to host cells. This organism, like Neisseria meningitidis, is also naturally competent for DNA uptake.

Subject: NC_007298:1418500 Dechloromonas aromatica RCB, complete genome

Lineage: Dechloromonas aromatica; Dechloromonas; Rhodocyclaceae; Rhodocyclales; Proteobacteria; Bacteria

General Information: This strain was enriched as a hydrocarbon-oxidizing chlorate-reducer from the Potomac River, Maryland, USA. This organism is the first one to have the capability of benzene oxidation in pure anaerobic culture by coupling it to nitrate reduction which is of importance due to the anaerobic environments often found in bioremediation projects. It can reduce perchlorate and chlorate to chloride. This organism may be used for bioremediation as it can oxidize aromatic hydrocarbon compounds, including benzene, in the absence of oxygen. Benzene is an important pollutant, and is used in many manufacturing processes and is a component of diesel fuel.