Query: NC_010994:57362 Rhizobium etli CIAT 652, complete genome Lineage: Rhizobium etli; Rhizobium; Rhizobiaceae; Rhizobiales; Proteobacteria; Bacteria General Information: It is a nitrogen-fixing symbiotic bacteria that interacts with the root of the common bean plant Phaseolus vulgaris. The molecular biology and evolution of R. etli and its relation to other nitrogen/fixing symbionts has been well studied. The genomic sequence will provide information on the process of symbiosis, on the genetic systems that allow the survival and adaptations of this bacteria to the soil, and on the evolutionary relationship and the symbiosis origin of this organism.
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General Information: Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.