Query: NC_010830:718614 Candidatus Amoebophilus asiaticus 5a2, complete genome Lineage: Amoebophilus asiaticus; Amoebophilus; Amoebophilaceae; Cytophagales; Bacteroidetes; Bacteria General Information: Candidatus Amoebophilus asiaticus 5a2 is an obligate endosymbiont found in Acanthamoeba sp. TUMSJ-321. This organism is a member of the highly diverse bacterial phylum Bacteroidetes which includes the endosymbiont lineages represented by the sister taxa Candidatus A. asiaticus and Candidatus Cardinium hertigii, a symbiont of arthropods.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.