Pre_GI: SWBIT SVG BLASTN

Query: NC_010717:4851000 Xanthomonas oryzae pv. oryzae PXO99A, complete genome

Lineage: Xanthomonas oryzae; Xanthomonas; Xanthomonadaceae; Xanthomonadales; Proteobacteria; Bacteria

General Information: This strain is a representative strain of race 6 isolated in the Philippines. This plant pathogen affects rice plants by causing leaf blight, a major problem in Asian countries where rice production occurs on an industrial scale. This organism enters the xylem and spreads throughout the vascular tissue of the plant, which results in wilting of the plant, or to leaf blight if the infection occurs later in development. This genus consists of plant-specific yellow-pigmented microbes, some of which are economically important phytopathogens that devastate crops such as citrus plants, rice, beans, grape, and cotton. These organisms are almost exclusively found associated with their plant hosts and are not found free in the soil. Xanthomonas oryzae contains two pathovars which cause enconomically significant diseases in rice. Xanthomonas oryzae pathovar oryzae causes bacterial leaf blight which is one of the most serious diseases of rice. This disease is common in temperate and tropical areas and can cause significant crop loss.

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BLASTN Alignment.txt

Subject: NC_004337:3590323 Shigella flexneri 2a str. 301, complete genome

Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated in 1984 from a patient in Beijing, China. It is similar to pathogenic Escherichia coli except for the more numerous insertion sequences and contains a virulence plasmid (pCP301). Causes enteric disease. Shigella This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.