Pre_GI: SWBIT SVG BLASTN

Query: NC_010694:2565580 Erwinia tasmaniensis, complete genome

Lineage: Erwinia tasmaniensis; Erwinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Erwinia tasmaniensis Et1/99 (DSM 17950) was isolated from apple flowers in Tasmania, Australia. Erwinia tasmaniensis has been isolated from apple and pear flowers and bark. This organism is not pathogenic to plants and appears to be a common epiphyte, colonizing plant surfaces.

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Subject: NC_003103:919000 Rickettsia conorii str. Malish 7, complete genome

Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.