Pre_GI: SWBIT SVG BLASTN

Query: NC_010677:214712 Francisella tularensis subsp. mediasiatica FSC147, complete genome

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This isolate was collected from a gerbil in central Asia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

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BLASTN Alignment.txt

Subject: NC_002620:705075 Chlamydia muridarum Nigg, complete genome

Lineage: Chlamydia muridarum; Chlamydia; Chlamydiaceae; Chlamydiales; Chlamydiae; Bacteria

General Information: This is a wild-type strain that is virulent in mice. Bacteria belonging to the Chlamydiales group are obligate intracellular parasites of eukaryotic cells. They are found within vertebrates, invertebrate cells, and amoebae hosts. Chlamydiae are one of the commonest causes of sexually transmitted diseases (STDs) and if left untreated may cause infertility in women. They are transmitted by direct contact or aerosols, and can cause various diseases, while also being able to coexist with the host in an apparently asymptomatic state. This organism causes pneumonitis (inflammation of lung tissue) in the mouse animal model and is used as a model organism to study pathogenesis.