Pre_GI: SWBIT SVG BLASTN

Query: NC_010655:1808657 Akkermansia muciniphila ATCC BAA-835, complete genome

Lineage: Akkermansia muciniphila; Akkermansia; Verrucomicrobiaceae; Verrucomicrobiales; Verrucomicrobia; Bacteria

General Information: This organism was isolated from human feces and is able to degrade mucin. Loss of this protective barrier may expose the gastrointestinal epithelial cells to pathogenic microorganisms or to the highly acidic gut environment. Akkermansia muciniphila is a member of the Verrucomicrobia which are also common in soil and water.

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BLASTN Alignment.txt

Subject: NC_002936:1004570 Dehalococcoides ethenogenes 195, complete genome

Lineage: Dehalococcoides mccartyi; Dehalococcoides; Dehalococcoidaceae; Dehalococcoidales; Chloroflexi; Bacteria

General Information: Dechlorinates tetrachloroethene. This organism was isolated from environments contaminated with organic chlorinated chemicals such as tetrachloroethene (PCE) and trichloroethane (TCE), common contaminants in the anaerobic subsurface. There are at least 15 organisms from different metabolic groups, halorespirators, acetogens, methanogens and facultative anaerobes, that are able to metabolize PCE. Some of these organisms couple dehalogenation to energy conservation and utilize PCE as the only source of energy while others dehalogenate tetrachloroethene fortuitously. This non-methanogenic, non-acetogenic culture is able to grow with hydrogen as the electron donor, indicating that hydrogen/PCE serves as an electron donor/acceptor for energy conservation and growth. This organism can only grow anaerobically in the presence of hydrogen as an electron donor and chlorinated compounds as electron acceptors. Dehalococcoides ethenogenes is typically found at sites contaminated with chlorinated solvents, and have been independently isolated in dozens of sites across the USA.