Query: NC_010655:2065567 Akkermansia muciniphila ATCC BAA-835, complete genome
Lineage: Akkermansia muciniphila; Akkermansia; Verrucomicrobiaceae; Verrucomicrobiales; Verrucomicrobia; Bacteria
General Information: This organism was isolated from human feces and is able to degrade mucin. Loss of this protective barrier may expose the gastrointestinal epithelial cells to pathogenic microorganisms or to the highly acidic gut environment. Akkermansia muciniphila is a member of the Verrucomicrobia which are also common in soil and water.
Subject: NC_013316:1 Clostridium difficile R20291, complete genome
Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria
General Information: Clostridium difficile R20291 was isolated in Stoke Mandeville Hospital, UK in 2006 and is closely related to the North American hypervirulent BI strains. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.