Query: NC_010524:4402478 Leptothrix cholodnii SP-6, complete genome Lineage: Leptothrix cholodnii; Leptothrix; Comamonadaceae; Burkholderiales; Proteobacteria; Bacteria General Information: Leptothrix cholodnii SP-6 was isolated from water and flocculent from an artificial iron seep in Ithaca, NY, USA. Leptothrix cholodnii, like other Leptothrix species is an iron- and manganese-oxidizing, sheathed bacterium common in organic rich aquatic environments. Iron oxides and manganese oxides often coat the sheathes of these organisms.
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General Information: A serum-resistant streptomycin-resistant proline-requiring strain isolated from a patient with disseminated gonococcal infections. Causes gonorrhea. One of two pathogenic Neisseria, this species causes the sexually transmitted disease (STD) gonorrhea, which is the leading reportable STD in adults in the USA. This human-specific organism colonizes and invades the mucosal surface of the urogenital epithelium, crosses the epithelial barrier, and ends up multiplying on the basement membrane. The Opa proteins are responsible for the opaque colony phenotype due to the tight junctions between adjacent Neisseria, and are also responsible for tight adherence to host cells. This organism, like Neisseria meningitidis, is also naturally competent for DNA uptake.