Pre_GI: SWBIT SVG BLASTN

Query: NC_010519:1963256 Haemophilus somnus 2336 chromosome, complete genome

Lineage: Histophilus somni; Histophilus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: This strain was isolated from the lung of a calf which had pneumonia. A group of organisms that are either obligate parasites or commensal organisms found in animal mucous membranes. Almost all species require the presence of important growth factors found in the blood of their hosts, including either X factor (protoporphyrin IX or heme) or V factor (nicotinamide adenine dinucleotide (NAD or NADP)). This organism is a major cause of disease in feedlot cattle. It causes constriction of blood vessels supplying major organs, restricting blood supply which leads to reduced oxygen delivery, and leads to tissue damage and death. The diseases that result are pneumonia, arthritis, myocarditis (inflammation of heart muscle), and reproductive problems resulting in the loss of millions of dollars in animals each year.

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BLASTN Alignment.txt

Subject: NC_008782:1510000 Acidovorax sp. JS42, complete genome

Lineage: Acidovorax; Acidovorax; Comamonadaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: Acidovorax sp. JS42, formerly Pseudomonas sp. JS42, was isolated from nitrobenzene-contaminated sediment and is capable of using 2-nitrotolulene as a sole carbon and energy source. 2-nitrotolulene, a nitroaromatic compound, is used in the manufacture of dyes, pigments and explosives. Nitroaromatic compounds, which contain an aromatic ring with one or more nitro groups attached, are a significant contaminant in industrial soils. Acidovorax sp. JS42 degrades 2-nitrotolulene by first removing the nitro moiety producing 3-methylcatechol. The enzyme involved in this process, 2-nitrotolulene dioxygenase, has been purified and characterized.