Query: NC_010519:1873190 Haemophilus somnus 2336 chromosome, complete genome Lineage: Histophilus somni; Histophilus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria General Information: This strain was isolated from the lung of a calf which had pneumonia. A group of organisms that are either obligate parasites or commensal organisms found in animal mucous membranes. Almost all species require the presence of important growth factors found in the blood of their hosts, including either X factor (protoporphyrin IX or heme) or V factor (nicotinamide adenine dinucleotide (NAD or NADP)). This organism is a major cause of disease in feedlot cattle. It causes constriction of blood vessels supplying major organs, restricting blood supply which leads to reduced oxygen delivery, and leads to tissue damage and death. The diseases that result are pneumonia, arthritis, myocarditis (inflammation of heart muscle), and reproductive problems resulting in the loss of millions of dollars in animals each year.
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General Information: This bacterium was isolated from a bovine rumen. Succinic acid producing bacterium. This bacterium is able to produce a large amount of succinic acid from readily available agricultural byproducts. Succinic acid is an important component in the manufacture of synthetic resins and biodegradable polymers. Mannheimia succiniciproducens can grow on media which includes whey, a byproduct of the cheese industry which is normally discarded, and corn steep liquor (CSL), which is a byproduct of corn starch production. The organism has been able to produce production-level amounts of succinic acid in both batch and continuous cultures in media containing these inexpensive components.