Query: NC_010503:327517 Ureaplasma parvum serovar 3 str. ATCC 27815 chromosome, complete Lineage: Ureaplasma parvum; Ureaplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria General Information: This organism (Ureaplasma urealyticum biovar 1) is normally found as a commensal organism in the human genital tract. As an opportunistic pathogen, it can cause a sexually-transmitted disease and is recognized as causing non-chlamydial non-gonococcal urethritis. It can also cause obstetric complications in pregnant women, severe infections in infants, as well as meningitis. Like other Mollicutes, it is a wall-less bacterium and has undergone marked genome reduction. This organism appears to generate ATP through the hydrolysis of urea by the urease enzyme.
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General Information: This organism causes arthritis in both rats and mice. Strains of Mycoplasma arthritidis can be virulent or avirulent depending, in part, on the presence of the MAV1 bacteriophage. This genus currently comprizes more than 120 obligate parasitic species found in the wide spectrum of hosts, including humans, animals, insects and plants. The primary habitats of human and animal mycoplasmas are mucouse membranes of the respiratory and urogenital tracts, eyes, mammary glands and the joints. Infection that proceeds through attachment of the bacteria to the host cell via specialized surface proteins, adhesins, and subsequent invation, results in prolonged intracellular persistence that may cause lethality. Once detected in association with their eukaryotic host tissue, most of mycoplasmas can be cultivated in the absence of a host if their extremely fastidious growth requirements are met.