Pre_GI: SWBIT SVG BLASTN

Query: NC_010337:2339056 Heliobacterium modesticaldum Ice1, complete genome

Lineage: Heliobacterium modesticaldum; Heliobacterium; Heliobacteriaceae; Clostridiales; Firmicutes; Bacteria

General Information: Heliobacterium modesticaldum strain Ice1, the type strain of this species, was isolated from Icelandic hot spring volcanic soils. It grows optimally above 50 degrees Celsius, grows best photoheterotrophically, but can grow in the dark chemotrophically on pyruvate. Phototrophic thermophile. This organism is an anoxygenic phototroph isolated from hot spring microbial mats and volcanic soil. Cell wall structure, the ability to form endospores, and 16S ribosomal RNA analysis place Heliobacterium modesticaldum in a family of phototrophic bacteria related to the Clostridia. Heliobacterium modesticaldum is able to fix nitrogen and may contribute significantly to the nitrogen availability in microbial mats.

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BLASTN Alignment.txt

Subject: NC_013316:3056925 Clostridium difficile R20291, complete genome

Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium difficile R20291 was isolated in Stoke Mandeville Hospital, UK in 2006 and is closely related to the North American hypervirulent BI strains. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.