Query: NC_010336:213148 Francisella philomiragia subsp. philomiragia ATCC 25017, complete Lineage: Francisella philomiragia; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria General Information: Francisella philomiragia subsp. philomiragia ATCC 25017 was isolated from water in the Bear River Refuge in Utah, USA. Causes disease in humans and fish. Francisella philomiragia, formerly Yersinia philomiragia, has been isolated from water, muskrats, fish and humans. F. philomiragia is able to cause an often fatal bacteremia in people with chronic granulomatous disease. This supspecies can also cause pneumonia in near-drowning victims.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: This organism is the endosymbiont of the American cockroach, Periplaneta americana. It is a Gram-negative maternally inherited bacteria which lives in specialized cells in the host's abdominal fat body. Phylogenetic analyses for the Blattabacterium-cockroach symbiosis supports the hypothesis of co-evolution between symbionts and hosts dating back to more than 140 million years ago. Cockroaches are omnivorous insects, often subsisting on a nitrogen-poor diet, and Blattabacterium have been hypothesized to participate in uric acid degradation, nitrogen assimilation, and nutrient provisioning. Genome sequencing and metabolic reconstruction shows that Blattabacterium can recycle nitrogen from urea and ammonia, which are uric acid degradation products, into glutamate, using urease and glutamate dehydrogenase, and thus would be able to provide its host with some essential amino acids, vitamins and cofactors. The bacterium relies on asparagine and glutamine supplied by the host; it may be able to make proline from arginine via the urea cycle.