Pre_GI: SWBIT SVG BLASTN

Query: NC_010280:769639 Chlamydia trachomatis L2b/UCH-1/proctitis, complete genome

Lineage: Chlamydia trachomatis; Chlamydia; Chlamydiaceae; Chlamydiales; Chlamydiae; Bacteria

General Information: This strain is a variant of the L2 serovar. Serovar L2 strains are associated with sexually transmitted infections and cause lymphogranuloma vernerum, a systemic infection involving the lymph nodes. Chlamydia trachomatis L2b/UCH-1/proctitis was isolated from a recent outbreak of proctitis in Europe. Causes disease in either the eye or the urogenital tract. Bacteria belonging to the Chlamydiales group are obligate intracellular parasites of eukaryotic cells. They are found within vertebrates, invertebrate cells, and amoebae hosts. Chlamydiae are one of the commonest causes of sexually transmitted diseases (STDs) and if left untreated may cause infertility in women. They are transmitted by direct contact or aerosols, and can cause various diseases, while also being able to coexist with the host in an apparently asymptomatic state. Chlamydia trachomatis causes infection that leads to blindness and sexually transmitted diseases in humans. There are 15 serovariants that preferentially cause disease in either the eye or the urogenital tract. The trachoma (infection of the mucous membrane of the eyelids) biovars are noninvasive and can cause blinding trachoma (variants A, B, Ba, and C), or sexually transmitted diseases (variants, D, E, F, G, H, I, J, and K). The lymphogranuloma venereum biovars (variants L1, L2, and L3) can cross the epithelial cells of mucous membranes and then travel through the lymphatic system where they multiply within mononuclear phagocytes found within the lymph nodes.

Subject: NC_010611:31976 Acinetobacter baumannii ACICU, complete genome

Lineage: Acinetobacter baumannii; Acinetobacter; Moraxellaceae; Pseudomonadales; Proteobacteria; Bacteria

General Information: Acinetobacter baumannii strain ACICU (also called H34) was isolated from an outbreak in an intensive care unit in Rome, Italy. This bacterium is commonly isolated from the hospital environment and hospitalized patients. It is an aquatic organism, and is often cultured from liquid medical samples such as respiratory secretions, wounds, and urine. Acinetobacter also colonizes irrigating solutions and intravenous solutions. Although it has low virulence, it is capable of causing infection. Most isolates recovered from patients represent colonization rather than infection. When infections do occur, they usually occur in the blood, or in organs with a high fluid content, such as the lungs or urinary tract.Infections by this organism are becoming increasingly problematic due to the high number of resistance genes found in clinical isolates. Some strains are now resistant to all known antibiotics. Most of these genes appear to have been transferred horizontally from other organisms.