Pre_GI: SWBIT SVG BLASTN

Query: NC_010263:167450 Rickettsia rickettsii str. Iowa, complete genome

Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Causative agent for Rocky Mountain Spotted Fever. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

- Sequence; - BLASTN hit (Low score = Light, High score = Dark)
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BLASTN Alignment.txt

Subject: NC_010981:594197 Wolbachia pipientis, complete genome

Lineage: Wolbachia endosymbiont of Culex quinquefasciatus; Wolbachia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This bacterial endosymbiont was isolated from the preblastoderm embryos of the Pel strain of Culex quinquefasciatus mosquitoes. This group of bacteria are associated with a variety of invertebrate species, some as pathogens, some in a symbiotic or other type of relationship. Typically these organisms are transmitted maternally from mother to daughter transovarially (through the egg) although these bacteria can affect their hosts reproductive capabilities in order to enhance transmission. The net outcome is the increase of hosts carrying the bacteria in the next generation, thereby increasing transmission.