Pre_GI: SWBIT SVG BLASTN

Query: NC_010263:167450 Rickettsia rickettsii str. Iowa, complete genome

Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Causative agent for Rocky Mountain Spotted Fever. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

- Sequence; - BLASTN hit (Low score = Light, High score = Dark)
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BLASTN Alignment.txt

Subject: NC_006361:4098469 Nocardia farcinica IFM 10152, complete genome

Lineage: Nocardia farcinica; Nocardia; Nocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This type strain was isolated from the bronchus of a male Japanese patient. Opportunistic human pathogen. This genus was originally described from specimens isolated by plating soil suspensions on diagnostic sensitivity test plates augmented with antifungal agents. Organisms in this genus cause opportunistic human pulmonary and systemic nocardiosis. This can complicate existing debilitating conditions such as leukemia, lymphoma, or other neoplasms, or illnesses in patients with compromised immune systems.