Pre_GI: SWBIT SVG BLASTN

Query: NC_010263:167450 Rickettsia rickettsii str. Iowa, complete genome

Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Causative agent for Rocky Mountain Spotted Fever. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

- Sequence; - BLASTN hit (Low score = Light, High score = Dark)
- hypothetical protein; - cds: hover for description

BLASTN Alignment.txt

Subject: NC_002976:177282 Staphylococcus epidermidis RP62A, complete genome

Lineage: Staphylococcus epidermidis; Staphylococcus; Staphylococcaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain is a strongly adherent, slime-producing, pathogenic strain isolated from a patient with intravascular catheter-associated sepsis. Common skin bacterium. Staphylcocci are generally found inhabiting the skin and mucous membranes of mammals and birds. Some members of this genus can be found as human commensals and these are generally believed to have the greatest pathogenic potential in opportunistic infections. This organism is the most prevalent and persistent Staphylococcus species on human skin. Has emerged as a common cause of nosocomial (hospital-acquired) infections, including catheter-associated infections and septicemia, particularly in immunocompromised patients. Highly resistant to many antibiotics including penicillins and cephalosporins.