Pre_GI: SWBIT SVG BLASTN

Query: NC_010263:278463 Rickettsia rickettsii str. Iowa, complete genome

Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Causative agent for Rocky Mountain Spotted Fever. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

Subject: NC_014836:1180454 Desulfurispirillum indicum S5 chromosome, complete genome

Lineage: Desulfurispirillum indicum; Desulfurispirillum; Chrysiogenaceae; Chrysiogenales; Chrysiogenetes; Bacteria

General Information: Environment: Fresh water; Temp: Mesophile. This is the first cultured species of the proposed new genus "Desulfurispirillum", and the sequencing of its genome will expand the range of experimental approaches that researchers can use to characterize its metabolic pathways for energy production and understand how these pathways are regulated. This organism is notable for its ability to reduce selenate to selenite and further to insoluble elemental selenium, in a process called dissimilatory selenate reduction.