Pre_GI: SWBIT SVG BLASTN

Query: NC_010162:573709 Sorangium cellulosum 'So ce 56', complete genome

Lineage: Sorangium cellulosum; Sorangium; Polyangiaceae; Myxococcales; Proteobacteria; Bacteria

General Information: Sorangium cellulosum 'So ce 56' produces a large number of bioactive compounds, such as, the antifungal soraphen and the anticancer agent epothilone. This organism, like other myxobacteria, undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. The motility system is not dependent on flagella like most bacteria, but instead relies on twitching pili: short extracellular appendages that may function analogously to oars in a rowboat. The myxobacteria have proved to be a rich source of novel natural products. Sorangium cellulosum produces a number of antibacterial, antifungal and cytotoxic substances which are being studies for therapeutic applications.

Subject: NC_013169:2147111 Kytococcus sedentarius DSM 20547, complete genome

Lineage: Kytococcus sedentarius; Kytococcus; Dermacoccaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Country: USA; Temp: Mesophile; Temp: 28 - 36C; Habitat: Marine, Skin microflora. Strain DSM 20547, the type strain, is a free-living, nonmotile, Gram-positive bacterium, originally isolated from a marine environment in about 1944. It grows as spherical/coccoid and occurs predominantly in tetrads which can be arranged in cubical packets. It is non-encapsulated and does not form endospores, is strictly aerobic and chemoorganotrophic, requires methionine and other amino acids for growth, and grows well in NaCl at concentrations up to 10% (w/v). This organism is a normal commensal of human skin, however has been implicated in pitted keratolysis, pneumonia, and other opportunistic infections.