Query: NC_010125:74904 Gluconacetobacter diazotrophicus PAl 5, complete genome Lineage: Gluconacetobacter diazotrophicus; Gluconacetobacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria General Information: Gluconacetobacter diazotrophicus strain PAL5 (ATCC 49037) was isolated from sugarcane roots in Brazil and will be used for comparative analysis. Nitrogen-fixing plant symbiont. This acid-tolerant organism is endophytic and colonizes internal plant tissues, establishing a symbiotic relationship with its host. This bacterium has been found in sugarcane, coffee, rice, tea, and other plants. The nitrogen-fixation systems of the bacterium provide the plant with essential nitrogenous compounds while the plant provides a protected environment for the bacterium to grow in. Nitrogen-fixation is important for sugarcane production, and this organism can fix nitrogen even in the presence of nitrate.
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General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.