Pre_GI: SWBIT SVG BLASTN

Query: NC_010120:1065833 Neisseria meningitidis 053442, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Subject: NC_009348:3819271 Aeromonas salmonicida subsp. salmonicida A449, complete genome

Lineage: Aeromonas salmonicida; Aeromonas; Aeromonadaceae; Aeromonadales; Proteobacteria; Bacteria

General Information: Aeromonas salmonicida subsp. salmonicida A449 was isolated from a brown trout with furunculosis. The agent of furunculosis, a major cause of mortality among salmonid fishes. This bacterium is the causal agent of furunculosis. Although it was discovered nearly 100 years ago, it is not known how the diesase is spread. Furunculosis is temperature sensistive, with acute cases occurring when the water is above 20 degrees C and chronic cases developing at temperatures below 13 degrees C. The acute form of the disease causes the fish to turn a dark color and stop eating.