Pre_GI: SWBIT SVG BLASTN

Query: NC_010067:4149298 Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, complete

Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This subspecies (IIIa) is usually found associated with reptiles, although contact with infected animals can result in the spread of the organism to humans or animals such as turkeys. This strain was originally isolated from a cornsnake in 1986 in Oregon, USA. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

Subject: NC_014932:1232346 Bartonella clarridgeiae 73, complete genome

Lineage: Bartonella clarridgeiae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella clarridgeiae was first identified from a case of cat scratch fever in a veterinarian who had been bitten by a cat. This organism has subsequently been identified in both cats and dogs. Cats, which are infected by fleas carrying the bacteria, in turn infect humans when scratching or biting them, hence the name. A small red bump forms at the site of infection, followed 2-3 weeks later by a painful swelling of the lymph node. In immunocompromized patients, more severe progress may be observed, including encephalitis, swelling of the spleen, and heart valve infection. Approximately 24 000 cases are reported in the US each year.