Query: NC_009921:6421387 Frankia sp. EAN1pec, complete genome Lineage: Frankia; Frankia; Frankiaceae; Actinomycetales; Actinobacteria; Bacteria General Information: This strain was isolated at the Kettering Research Laboratory in Ohio, USA by M. Lalonde in 1978. It is resistant to lincomycin, kasugamycin, novobiocin, and, like many actinomycetes, to nalidixic acid. This strain is also resistant to elevated levels of lead, chromate, and arsenate.
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General Information: This organism was first isolated from the soil in Vineland, New Jersey, although it is found worldwide. It is a large obligate aerobe that has one of the highest respiratory rates of any organism. Azotobacter vinelandii also produces a number of unusual nitrogenases which allow it to fix atmospheric nitrogen to ammonia, a compound it can then use as a nitrogen source. It protects the oxygen-sensitive nitrogenase enzymes through its high respiratory rate, which sequesters the nitrogenase complexes in an anoxic environment. This organism has a number of unusual characteristics. Under extreme environmental conditions, the cell will produce a cyst that is resistant to dessication and is surrounded by two capsular polysaccharide layers. This organism produces two industrially important polysaccharides, poly-beta-hydroxybutyrate (PHB) and alginate. PHB is a thermoplastic biopolymer, and alginate is used in the food industry. Alginate is also used by the pathogen Pseudomonas aeruginosa to infect the lungs of cystic fibrosis patients.