Query: NC_009785:2049395 Streptococcus gordonii str. Challis substr. CH1, complete genome Lineage: Streptococcus gordonii; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria General Information: Normal human oral flora. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. Streptococcus gordonii is a commensal member of the human oral flora. It initiates the formation of biofilms on tooth surfaces known as dental plaque, which is strongly associated with the development of dental cavities (caries) and gum disease. It is a frequent causative agent of bacterial endocarditis (inflammation of the membrane lining the heart) which often occurs as a result of oral trauma, allowing S. gordonii to invade the bloodstream and colonize the heart.
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General Information: This strain is a serotype V clinical isolate and is the most common type amoung GBS-infected (group B streptococcal) non-pregnant adults. Causes meningitis and sepsis in newborns. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. This organism is the leading cause of meningitis and sepsis in newborns. Additionally this organism is the cause of serious infections in immunocompromised adults. Able to asymptomatically colonize human skin and mucous membranes. This organism is also implicated in cases of mastitis in cows.