Pre_GI: SWBIT SVG BLASTN

Query: NC_009749:289695 Francisella tularensis subsp. holarctica FTA, complete genome

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: Isolated from an immunocompetent 56-year old male with bacteremic pneumonia in France. Francisella tularensis is a non-motile, aerobic, rod-shaped Gram-negative bacterium and is the causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

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BLASTN Alignment.txt

Subject: NC_014733:2201485 Methylovorus sp. MP688 chromosome, complete genome

Lineage: Methylovorus; Methylovorus; Methylophilaceae; Methylophilales; Proteobacteria; Bacteria

General Information: Methylotrophic bacteria are a group of bacteria which are able to grow aerobically at the expense of methanol as the sole source of carbon and energy, and therefore could serve as biocatalysts for the conversion of methanol to commercially valuable multicarbon compounds like amino acids and cytochromes. Pink-pigmented facultative methylotrophs of the genus Methylovorus are ubiquitous in soil, air and water environments. The MP688 strain was isolated from soil as an PQQ producer.