Pre_GI: SWBIT SVG BLASTN

Query: NC_009749:289695 Francisella tularensis subsp. holarctica FTA, complete genome

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: Isolated from an immunocompetent 56-year old male with bacteremic pneumonia in France. Francisella tularensis is a non-motile, aerobic, rod-shaped Gram-negative bacterium and is the causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

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BLASTN Alignment.txt

Subject: NC_014212:319815 Meiothermus silvanus DSM 9946 chromosome, complete genome

Lineage: Meiothermus silvanus; Meiothermus; Thermaceae; Thermales; Deinococcus-Thermus; Bacteria

General Information: Isolation: Hot spring; Country: Portugal; Temp: Thermophile; Temp: 50C; Habitat: Hot spring. An aerobic, thermophilic, nonmotile Gram-negative bacterium isolated from the hot spring located at the end of a 450 m tunnel and from thermal water piped to a spa at Vizela in northern Portugal. M. silvanus is of special interest as it causes colored biofilms in the paper making industry and may thus be of economic importance as a biofouler. M. silvanus has also been detected in the gut of an invasive wood-boring beetle and in seawater adjacent to a Pacillopora meandrina coral colony at Palmyra Atoll.