Pre_GI: SWBIT SVG BLASTN

Query: NC_009749:289695 Francisella tularensis subsp. holarctica FTA, complete genome

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: Isolated from an immunocompetent 56-year old male with bacteremic pneumonia in France. Francisella tularensis is a non-motile, aerobic, rod-shaped Gram-negative bacterium and is the causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

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BLASTN Alignment.txt

Subject: NC_007298:1129889 Dechloromonas aromatica RCB, complete genome

Lineage: Dechloromonas aromatica; Dechloromonas; Rhodocyclaceae; Rhodocyclales; Proteobacteria; Bacteria

General Information: This strain was enriched as a hydrocarbon-oxidizing chlorate-reducer from the Potomac River, Maryland, USA. This organism is the first one to have the capability of benzene oxidation in pure anaerobic culture by coupling it to nitrate reduction which is of importance due to the anaerobic environments often found in bioremediation projects. It can reduce perchlorate and chlorate to chloride. This organism may be used for bioremediation as it can oxidize aromatic hydrocarbon compounds, including benzene, in the absence of oxygen. Benzene is an important pollutant, and is used in many manufacturing processes and is a component of diesel fuel.