Pre_GI: SWBIT SVG BLASTN

Query: NC_009749:289695 Francisella tularensis subsp. holarctica FTA, complete genome

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: Isolated from an immunocompetent 56-year old male with bacteremic pneumonia in France. Francisella tularensis is a non-motile, aerobic, rod-shaped Gram-negative bacterium and is the causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

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BLASTN Alignment.txt

Subject: NC_005773:4028500 Pseudomonas syringae pv. phaseolicola 1448A, complete genome

Lineage: Pseudomonas savastanoi; Pseudomonas; Pseudomonadaceae; Pseudomonadales; Proteobacteria; Bacteria

General Information: This is gram-negative bacterium pathogenic in plants. Characterized as causing halo blight on beans (Phaseolus vulgaris). This bacterium is closely related to Pseudomonas syringae pv. glycinea and Pseudomonas syringae pv. savastanoi and produces phaseolotoxin, which is a phytotoxin. Strain 1448A is a natural occurring rifampicin-resistant mutant strain and contains a non-functional homolog of avrPphE.