Query: NC_009718:1207360 Fervidobacterium nodosum Rt17-B1, complete genome
Lineage: Fervidobacterium nodosum; Fervidobacterium; Thermotogaceae; Thermotogales; Thermotogae; Bacteria
General Information: Fervidobacterium nodosum is a thermophilic, Gram-negative, motile, non-sporulating, glycolytic, obligately anaerobic rod that exists singly, in pairs or in chains. Fervidobacterium nodosum was isolated from a hot spring in New Zealand. Its optimal growth temperature is 65 to 70 degrees Celsius. The cellular morphology of this organism, a member of the Thermotogales, is characterized by a terminal spherical extension of the cell envelope.
Subject: NC_009749:221311 Francisella tularensis subsp. holarctica FTA, complete genome
Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria
General Information: Isolated from an immunocompetent 56-year old male with bacteremic pneumonia in France. Francisella tularensis is a non-motile, aerobic, rod-shaped Gram-negative bacterium and is the causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.