Pre_GI: SWBIT SVG BLASTN

Query: NC_009708:372422 Yersinia pseudotuberculosis IP 31758 chromosome, complete genome

Lineage: Yersinia pseudotuberculosis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is serotype 1b and was isolated in 1966 from the stools of a patient presenting with scarlet-like fever in the Primorski region of the former USSR. Environmental bacterium that causes gastrointestinal disease. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. This organism was first isolated in 1883 by Malassez and Vignal and is termed pseudotuberculosis since it causes lesions in the lung that are similar to those observed during tuberculosis infection. It is ubiquitous in the environment and is a food and waterborne pathogen that affects animals as well as humans by causing gastroenteritis like Yersinia enterocolitica.

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BLASTN Alignment.txt

Subject: NC_012962:293976 Photorhabdus asymbiotica, complete genome

Lineage: Photorhabdus asymbiotica; Photorhabdus; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is a North American clinical isolate from human blood. Photorhabdus asymbiota, formerly Xenorhabdus luminescens, has been isolated from human wound and blood infections often in association with spider bites. This species can also be isolated from the entomopathogenic nematode Heterorhabditis indica. Photorhabdus asymbiota is divided into two subspecies, subsp. australis which contains the Australian clinical isolates and subsp. asymbiota which contains the North American isolates. Photorhabdus is currently subdivided into three species, luminescens, temperate and asymbiotica all of which have been isolated as symbionts of heterorhabditid nematodes. This organism is unusual in that it is symbiotic within one insect, and pathogenic in another, the only organism that is known to exhibit this dual phenotype.