Query: NC_009615:1734752 Parabacteroides distasonis ATCC 8503 chromosome, complete genome
Lineage: Parabacteroides distasonis; Parabacteroides; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria
General Information: Normal gastrointestinal bacterium. This group of microbes constitute the most abundant members of the intestinal microflora of mammals. Typically they are symbionts, but they can become opportunistic pathogens in the peritoneal (intra-abdominal) cavity. Breakdown of complex plant polysaccharides such as cellulose and hemicellulose and host-derived polysaccharides such as mucopolysaccharides is aided by the many enzymes these organisms produce. Parabacteroides distasonis is one of the most common fecal isolates, however, this organism is rarely isolated from clinical specimens.
Subject: NC_014014:153837 Mycoplasma crocodyli MP145 chromosome, complete genome
Lineage: Mycoplasma crocodyli; Mycoplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria
General Information: Mycoplasma crocodyli was isolated from the joint of a crocodile with exudative polyarthritis. The siblingspecies of M. crocodyli, Mycoplasma alligatoris causes acute lethalprimary infection of susceptible hosts, notably American alligators.This pathogen is studied to understand the mechanisms and evolutionaryorigins of that virulence. A genome survey indicated that M. alligatorisuses sialidase (Nanl) and hyaluronidase (NagH) to generate fuel forglycolysis from host cell glycans. M. crocodyli, which does not causedisease in American alligators, possesses NagH but not Nanl, so damageto the host's extracellular matrix alone cannot explain the particularvirulence of M. alligatoris.