Query: NC_009515:510121 Methanobrevibacter smithii ATCC 35061, complete genome Lineage: Methanobrevibacter smithii; Methanobrevibacter; Methanobacteriaceae; Methanobacteriales; Euryarchaeota; Archaea General Information: Methanobrevibacter smithii ATCC 35061 (DSM 861) (strain PS) was isolated from a sewage digester in Gainesville, Florida, USA. Sewage digester isolate. Human gut methanogen. Methanobrevibacter smithii can be isolated from anoxic environments such as anaerobic digesters, anaerobic soil and sediment, and the gastrointestinal tracts of humans, ruminants and other animals. This organism is the dominant archaeal symbiont found in the human gut.
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General Information: Lactobacillus gasseri ATCC 33323 is a human isolate and is the type strain. This organism has been shown to have probiotic activities such as production of bacteriocins, macrophage stimulation and adherence to intestinal tissues. Normal gastrointestinal bacterium. They are commonly found in the oral, vaginal, and intestinal regions of many animals. They are important industrial microbes that contribute to the production of cheese, yogurt, and other products such as fermented milks, all stemming from the production of lactic acid, which inhibits the growth of other organisms as well as lowering the pH of the food product. Industrial production requires the use of starter cultures, which are carefully cultivated, created, and maintained, which produce specific end products during fermentation that impart flavor to the final product, as well as contributing important metabolic reactions, such as the breakdown of milk proteins during cheese production. The end product of fermentation, lactic acid, is also being used as a starter molecule for complex organic molecule syntheses. Lactobacillus gasseri is a rod-shaped, gram-positive anaerobe. Of the lactobacilli, it is the most amenable to DNA introduction and manipulation which should prove useful in the functional genomic analysis of this species. It has been shown to be an effective probiotic in suppressing Helicobacter pylori infections in humans.