Pre_GI: SWBIT SVG BLASTN

Query: NC_009505:264963 Brucella ovis ATCC 25840 chromosome I, complete sequence

Lineage: Brucella ovis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This strain was isolated from sheep tissue in Australia. Causes brucellosis in sheep. This organism specifically affects sheep, causing ovine brucellosis which results in significant economic losses. Infection by the organism can cause infertility in rams as the bacterium preferentially colonizes the genital tract, and causes inflammation of the epididymis which leads to necrotic lesions and a decrease in sperm numbers and motility. This bacterium, like other Brucella, is an intracellular pathogen that infects phagocytic cells such as macrophages. Bacterial cells produces a lipopolysaccharide that lacks O-antigen side chains, which results in a rough colony phenotype, and aids in differentiation as compared to other Brucella.

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BLASTN Alignment.txt

Subject: NC_012962:3864000 Photorhabdus asymbiotica, complete genome

Lineage: Photorhabdus asymbiotica; Photorhabdus; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is a North American clinical isolate from human blood. Photorhabdus asymbiota, formerly Xenorhabdus luminescens, has been isolated from human wound and blood infections often in association with spider bites. This species can also be isolated from the entomopathogenic nematode Heterorhabditis indica. Photorhabdus asymbiota is divided into two subspecies, subsp. australis which contains the Australian clinical isolates and subsp. asymbiota which contains the North American isolates. Photorhabdus is currently subdivided into three species, luminescens, temperate and asymbiotica all of which have been isolated as symbionts of heterorhabditid nematodes. This organism is unusual in that it is symbiotic within one insect, and pathogenic in another, the only organism that is known to exhibit this dual phenotype.