Query: NC_009454:1042592 Pelotomaculum thermopropionicum SI, complete genome Lineage: Pelotomaculum thermopropionicum; Pelotomaculum; Peptococcaceae; Clostridiales; Firmicutes; Bacteria General Information: This type strain was isolated from granular sludge from a thermophilic upflow anaerobic sludge blanket (UASB) reactor. It was isolated both in pure culture and in co-culture with methanogens. In syntrophic association with hydrogenotrophic methanogens, this species can utilize propionate, ethanol, lactate, ethylene glycol, 1-butanol, 1-propanol, 1-pentanol and 1,3-propanediol. This is the first mesophilic, syntropic propionate-oxidizing species known which is not a member of the delta-proteobacteria.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Causative agent for Rocky Mountain Spotted Fever. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.