Query: NC_009454:1042592 Pelotomaculum thermopropionicum SI, complete genome Lineage: Pelotomaculum thermopropionicum; Pelotomaculum; Peptococcaceae; Clostridiales; Firmicutes; Bacteria General Information: This type strain was isolated from granular sludge from a thermophilic upflow anaerobic sludge blanket (UASB) reactor. It was isolated both in pure culture and in co-culture with methanogens. In syntrophic association with hydrogenotrophic methanogens, this species can utilize propionate, ethanol, lactate, ethylene glycol, 1-butanol, 1-propanol, 1-pentanol and 1,3-propanediol. This is the first mesophilic, syntropic propionate-oxidizing species known which is not a member of the delta-proteobacteria.
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General Information: This strain (82-40) was isolated from the blood of a human patient who was having a renal transplant and is the best characterized isolate of this species.. The ratio of bloodstream infection to diarrheal illnesses for C. fetus is nearly 400-fold higher than for C. jejuni, indicating its marked propensity for invasive disease compared to C. jejuni. Causes infertility, infectious abortions in cattle, opportunistic human pathogen. This organism causes infertlity and infectious abortions in domesticated sheep, goats and cattle. It is an opportunistic pathogen in humans which can severely affect immunocompromised patients. Initially the bacterium can cause gastroenteritis, and then spread systemically throughout the blood (bacteremia) and cause septicemia, meningitis, and other systemic infections. This layer is essential for host colonization, and prevents complemented-mediated immune responses by inhibiting complement C3b binding.