Pre_GI: SWBIT SVG BLASTN

Query: NC_009381:3094939 Yersinia pestis Pestoides F chromosome, complete genome

Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Atypical strain isolated from the former Soviet Union, USSR. This strain lacks a plasminogen activator and is virulent by the aerosol route. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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BLASTN Alignment.txt

Subject: NC_007761:781210 Rhizobium etli CFN 42, complete genome

Lineage: Rhizobium etli; Rhizobium; Rhizobiaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: It is a nitrogen-fixing symbiotic bacteria that interacts with the root of the common bean plant Phaseolus vulgaris. P. etli and its relation to other nitrogen/fixing symbionts has been well studied. The genomic sequence will provide information on the process of symbiosis, on the genetic systems that allow the survival and adaptations of this bacteria to the soil, and on the evolutionary relationship and the symbiosis origin of this organism.