Pre_GI: SWBIT SVG BLASTN

Query: NC_009257:226417 Francisella tularensis subsp. tularensis WY96-3418 chromosome,

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human finger wound. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

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BLASTN Alignment.txt

Subject: NC_002928:507749 Bordetella parapertussis 12822, complete genome

Lineage: Bordetella parapertussis; Bordetella; Alcaligenaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: This strain was isolated from an infected infant in Germany in 1993. Causes respiratory illness in humans and sheep. This group of organisms is capable of invading the respiratory tract of animals and causing severe diseases. They express a number of virulence factors in order to do this including filamentous hemagglutins for attachment, cytotoxins, and proteins that form a type III secretion system for transport of effector molecules into host cells. Bordetella parapertussis can infect humans and sheep and it is unable to persist in the environment. This organism causes a respiratory disease similar to, but less severe than, Bordetella pertussis in humans and a chronic pneumonia in sheep.