Pre_GI: SWBIT SVG BLASTN

Query: NC_009142:6086000 Saccharopolyspora erythraea NRRL 2338, complete genome

Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.

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BLASTN Alignment.txt

Subject: NC_010407:151599 Clavibacter michiganensis subsp. sepedonicus chromosome, complete

Lineage: Clavibacter michiganensis; Clavibacter; Microbacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Causative agent of bacterial ring rot. Isolated from infected potato. This organism was first described and classified in 1914 as "Bacterium sepedonicus" and is considered a major plant pathogen. It is a phytopathogenic actinomycete that causes wilt and tuber rot in potato, which is a plant vascular disease with very high bacterial titers. Pathogenicity is believed to be associated with the presence of two plasmids, pCSL1 and pCSL2. This species is subdivided into five subspecies: michiganensis, sepedonicus, nebraskensis, tesselarius and insidiosus each of which infects specific hosts: tomato, potato, corn, wheat and alfalfa, respectively. Members of the Clavibacter genus are known to produce antimicrobial compounds.