Query: NC_009142:7820251 Saccharopolyspora erythraea NRRL 2338, complete genome Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: This strain was isolated from a green alder (Alnus crispa) growing in Tadoussac, Canada. These bacteria were originally linked to fungi, because of the mycelium-like filaments many of them form. This bacterium is able to establish a nitrogen-fixing symbiosis with alder (Alnus spp.) and myrtle (Myrica spp.), two pioneer plant genera of temperate regions, found on forest clearings, mine wastes, sand dunes and glacial moraines where nitrogen is the limiting factor. Frankia alni causes root hair deformation: it penetrates the cortical cells and induces the formation of nodules which resemble those induced by Rhizobium in legumes. These nodules are then colonized by vegetative hyphae (mycelium filaments) which differentiate into diazo-vesicles