Pre_GI: SWBIT SVG BLASTN

Query: NC_009142:7820251 Saccharopolyspora erythraea NRRL 2338, complete genome

Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.

Subject: NC_007973:1889076 Ralstonia metallidurans CH34 chromosome 1, complete sequence

Lineage: Cupriavidus metallidurans; Cupriavidus; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: This strain was first identified in the heavy metal-contaminated sludge of a settling tank in Belgium in the late 1970s. This organism, formerly Ralstonia metallidurans, is capable of growth in the presence of a large number of heavy metals including silver, cadmium, chromium, cobalt, copper, mercury, nickel, lead, thallium, and zinc.