Query: NC_009142:5425763 Saccharopolyspora erythraea NRRL 2338, complete genome
Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.
Subject: NC_011901:837085 Thioalkalivibrio sulfidophilus HL-EbGr7 chromosome, complete
Lineage: Thioalkalivibrio sulfidophilus; Thioalkalivibrio; Ectothiorhodospiraceae; Chromatiales; Proteobacteria; Bacteria
General Information: Obligately chemolithoautotrophic, haloalkaliphilic, mesophilic, microaerophilic and sulfur-oxidizing bacterium. Uses CO2 as a carbon source and reduced inorganic sulfur compounds as an energy source. Utilizes ammonium and urea, but not nitrate or nitrite, as a N-source. Isolated from a full-scale Thiopaq bioreactor in the Netherlands used to remove H2S from biogas. Thioalkalivibrio species are commonly isolated from soda lakes and tend to dominate the microbial community of hypersaline soda lakes. These organisms have a pH optimum of 10 and are able to oxidize hydrogen sulfide to elemental sulfur. Thioalkalivibrio species have also been isolated from sulfide oxidizing bioreactors which remove sulfide from refinery and natural gas.