Pre_GI: SWBIT SVG BLASTN

Query: NC_009142:2565561 Saccharopolyspora erythraea NRRL 2338, complete genome

Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.

Subject: NC_010364:733558 Halobacterium salinarum R1, complete genome

Lineage: Halobacterium salinarum; Halobacterium; Halobacteriaceae; Halobacteriales; Euryarchaeota; Archaea

General Information: Chemoheterotrophic obligate extreme halophilic archeon. Halobacterial species are obligately halophilic microorganisms that have adapted to optimal growth under conditions of extremely high salinity 10 times that of sea water. This bacterium (strain R1; DSM 671) is an obligately halophilic archeon and represents the type species for the genus Halobacterium. The first recorded isolation of this organism came from the spoilage of salted fish. It is also commonly found in neutral salt lakes, marine salterns, proteinaceous products heavily salted with crude solar salt and ancient evaporate deposits.