Pre_GI: SWBIT SVG BLASTN

Query: NC_009142:2565561 Saccharopolyspora erythraea NRRL 2338, complete genome

Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.

Subject: NC_009078:510525 Burkholderia pseudomallei 1106a chromosome II, complete sequence

Lineage: Burkholderia pseudomallei; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: Isolated from liver abscess from a 23-year old female patient in Thailand in 1993. This species is an opportunistic pathogen and can cause pneumonia, bacteremia, and melioidosis. It is normally found in terrestrial environments and has been recovered from rice paddies and moist tropical soil. It is endemic in Asia and Australia, but can be found in other parts of the world. The organism can exist intracellularly and can spread through the bloodstream (bacteremia)